(S)-3-Aminothiolane: A New Chiral Building Block
E.V.Dehmlow, R.Westerheide; Synthesis 1992, p. 947-949
The racemate of the title compound and the respective sulfone have been used extensively as building
blocks for diverse pharmacological agents, such as antitumor compounds, antiradiation compounds,
sweeteners, gastric antisecratory and antifertility agents, analogues of antibiotics, fungicides,
and others. We report here on a simple synthesis of the title compound which was discovered
incidentally in the course of another project.
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