Combinatorial Chemistry Review

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Introduction

  Principle of Combinatorial Chemistry

  Combinatorial Libraries

Combinatorial synthesis on solid phase

   Solid Phase Synthesis

Polymers

   Cross – Linked Polystyrene

   Polyamide Resins

   TentaGel Resins

The linker

   Carboxylic acid linkers

   Carboxamide linkers

   Alcohol Linkers

   Amine linkers

   Traceless linkers

Synthesis of a Combinatorial Library

   Synthesis of a Combinatorial Library

Determination of Product Structure

   Determination of Product Structure

   DNA – based encoding

   Peptide tag

   Mass encoding

   Hard Tag

   Radio-Frequency Encoding

Combinatorial Synthesis in Solution

   Solution Phase Synthesis

   Parallel Solution Synthesis

   Indexed Ñombinatorial Libraries

Application of Combinatorial Chemistry

   Transition-state analog HIV protease inhbitors

Conclusion

   Combinatorial chemistry: a Conclusion

Glossary

   Combinatorial Chemistry Glossary

   Terms Beginning With "A-B"

   Terms Beginning With "C"

   Terms Beginning With "D-E"

   Terms Beginning With "F"

   Terms Beginning With "G-I"

   Terms Beginning With "K-L"

   Terms Beginning With "M-O"

   Terms Beginning With "P"

   Terms Beginning With "R"

   Terms Beginning With "S"

   Terms Beginning With "T-X"

Articles Devoted to Combinatorial Chemistry

   High Throughput Screening and Combinatorial Chemistry Articles

   Second Page

   Third Page

   Fourth Page

News & Events

   Events in field of Drug Discovery

About Project

   About Combinatorial Chemistry Review

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Usefull Information

   Chemistry Articles

   (S)-3-Aminothiolane

   Cis-2,5-Disubstituted Tetrahydrofurans

   New synthesis of lactams and spirolactams.

   5-Substituted Pyrrolidinones

   Simple Synthesis of Indoles and 1-Acyl-3-Indolinones

   2-Substituted Indoles

   A Simple Synthesis of 2-Substituted Indoles

   Synthesis of Indole-2-carboxylic Esters

   Indole Synthesis

   Indoles and Oxindoles

   Synthesis of quinoline derivatives

   Substituted Quinoline N-Oxides

   Amino carbanions

   5,6-Dihydro-2(1H)-pyridinones

   vinyl isocyanates and enamines

   Lithioamine synthetic equivalents

   1-Acyldihidropyridines

   synthesis of (S)-(+)-cryptostyline

   6-Alkylpipecolic Acids

   A novel pyrazole synthesis

   Pyrazinyl and Quinoxalinyl Phenylmethanones

   Pyrido[4,3-c]pyridazine Ring

Link

   Web resources of interest to chemists